Rockefeller University Research Assistant in New York, New York
Job Title Research Assistant
Employment Status Full Time
Laboratory / Department Mammalian Cell Biology and Development
Our laboratory begins with molecular mechanisms, and we work our way to the genetic bases of human diseases that are caused by defects in the proteins we study. We have repeatedly used this reverse genetic approach to successfully elucidate the genetic bases of a variety of human and mouse disorders, ranging from blistering skin disorders and skin tumors/cancers, to a rare form of muscle degeneration and a sensory neurological disorder.
Will work as a part of highly talented team of molecular, cell, and developmental biologists seeking an understanding of the properties of adult skin stem cells and how aberrations in their biology can lead to skin disorders, including cancers. Will be responsible for the design of novel DNA constructs for genetic engineering in primary stem cells and/or in mice, design and optimization of reporter constructs and primers for genotyping, and CRISPR/Cas9 cloning and testing mouse founder lines for proper gene expression. Pending the science and experience, will be involved in related research projects.
Bachelor's degree in science or higher required. Must have strong molecular biology skills in designing and making DNA constructs and a minimum of 2 years' of research experience working in undergrad or postbac labs. Experience with CRISPR/Cas9 technology and tissue culture is a plus. Must be a fast learner and quick to transition to independence. Must thrive in a fast paced research lab and interact well with a dynamic group of postdoctoral researchers and students.