Rockefeller University Research Assistant, Human Genetics of Infectious Diseases in New York, New York
Job Title Research Assistant, Human Genetics of Infectious Diseases
Laboratory / Department Human Genetics of Infectious Diseases
The Laboratory of Human Genetics of Infectious Diseases studies the genetics of human predisposition to pediatric infectious diseases, particularly mycobacterial diseases, invasive pneumococcal diseases and herpes simplex encephalitis. It aims to identify Mendelian 'holes' in the immune defense of otherwise healthy children who are susceptible to specific infectious diseases, work that has profound implications for and has resulted in a paradigm shift in human clinical medicine and fundamental immunology. In the past decade, the laboratory has uncovered that single genetic lesions in children confer severe and selective vulnerability to certain illnesses, whereas corresponding infections in adults result more from polygenetic inheritance. This work not only blurs the distinction between patient-based Mendelian genetics and population-based complex genetics but has also provided experimental support for a unified theory of human infectious diseases.
The Research Assistant will work primarily under the direct supervision of a Senior Researcher of a lab investigating the human genetic basis of viral diseases and interact with other researchers of the group. Will be responsible for designing, carrying out, reporting, and recording experiments that aim to identify and characterize genetic disorders of the immune system. Responsibilities include analysis of databases, cloning, and sequencing DNA, setting up and analyzing PCR experiments, tissue culture, and functional studies of the signaling pathways involved in viral diseases from patients and healthy controls.
Bachelor's degree in science required; Master's degree and educational emphasis in biochemistry, molecular genetics, immunology, or related field preferred. Must have a minimum of three years of experience and be detail-oriented, have a strong sense of responsibility, and work as part of a team in a fast-paced environment. Strong interpersonal skills, communication skills, and computer proficiency are required. Experience with Western blot and flow cytometry methods preferred.
The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans