Organization Overview

Research in the Laboratory of Molecular Biology, led by Dr. Nathaniel Heintz, aims to identify the genes, circuits, cells, macromolecular assemblies, and individual molecules that contribute to the function of the mammalian brain and to its dysfunction in disease. Understanding the distinct classes of neurons and the circuits that control specific aspects of cognition and behavior can lead to more targeted treatments for central nervous system disorders.

Overview

We are looking for a highly motivated individual to work on a project that will study the molecular basis of selective cellular vulnerability in Huntington's disease. The goal of this project is to identify novel strategies to delay onset and/or slow progression of the disease.

Responsibilities

The person who will join our team will be responsible for:

• Preparing human brain samples (FFPE or frozen) for chromogenic and fluorescent immunohistochemistry and in situ hybridization

• Preparing solutions

• Performing routine stains

• Cover slipping slides

• Data entry

The opportunity to learn cutting-edge tissue-clearing techniques for 3D histology as well as an opportunity to learn how to operate a modern light-sheet microscope will be available.

Qualifications

• Bachelor's degree required

• Experience embedding and sectioning tissue is required as is familiarity with brightfield and confocal microscopes

• Familiarity with quantitative tissue analysis software such as Fiji (ImageJ) or HALO Imaging Software is a plus

• Candidate must be organized, have good communication skills, and keep clear, accurate records

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans.

Compensation Range: Min

USD $46,000.00/Yr.

Compensation Range: Max

USD $50,000.00/Yr.

Job Locations US-NY-New York

Category Science

Position Type Regular Full-Time