Rockefeller University Research Assistant in New York, New York
Job Title Research Assistant
Laboratory / Department Molecular and Cellular Neuroscience
The Laboratory of Molecular and Cellular Neuroscience studies the molecular defects responsible for neurological and psychiatric disorders including Alzheimer's disease, major depressive disorder, Parkinson's disease, and obsessive compulsive disorder, as well as the molecular mechanisms by which neuro- and psychoactive drugs produce their pharmacological actions in these disorders. Research from the laboratory has demonstrated that most neurotransmitters and neuromodulators achieve their actions and interactions on post-synaptic neurons through a process called "slow synaptic transmission." This process involves activation of highly complex signal transduction cascades. For the last 10 years, the group has applied this knowledge and developed a state-of-the-art methodologies (eg. BacTRAP), to the study of the molecular pathways behind various neurological and psychiatric disorders.
Under general direction, the Research Assistant will assist a Senior Research Associate in performing experiments aimed to understand the role of autophagy in neurodegenerative diseases. Will perform experiments using Western blotting, protein purification, cell culture, plasmid purification, PCR, animal model genotyping, ELISA, mice husbandry, and small molecule characterization. Will be responsible for routine lab maintenance as well as compiling, processing and analyzing data.
Bachelor's degree in science required; educational emphasis in biochemistry, neuroscience, or biology preferred. Must possess knowledge of laboratory procedures, willingness to work with small animals, excellent verbal and communication skills, and strong attention to detail. Experience with managing animal colonies preferred.